January 4, 2018

Phosadyl is a foundational supplement that Dr. Lieberman has carried in some form or another for nearly 20 years. This supplement supplies essential phospholipids, which are unique substances that form all cell membranes in humans, as well as the membrane around the nucleus of each cell. Phospholipids are fascinating in their structure: they aren’t true lipid or fat molecules because they have an extra phosphate group replacing one of the fatty acids, but that is what gives them their unique properties. The phosphate head of the phospholipid is hydrophilic or attracted to water, and the fatty acid tail is hydrophobic or repelled by water. In the presence of liquid, which is 90 percent of what we humans are made up of, the phospholipids all naturally line up in a double layer, with all their phosphate heads in one direction and all their fatty acid tails in another, towards the inside of the layer. This double layer of phospholipids is what forms the basis of the cell membrane. We tend to think of our cells as these very distinct little spheres with strong walls around them, but actually human cell membranes are more the consistency of heavy olive oil and are a constantly moving mosaic of phospholipids!

This double layer of phospholipids helps give cell membranes what we call “selective permeability,” meaning that substances beneficial to the cell are able to diffuse through or be actively taken up by the cell membrane, and harmful substances or pathogens are usually not. Many beneficial substances are biochemically suited to make it through both the hydrophilic end of the phospholipid layer and the fatty acid end within the layer. Other beneficial substances such as hormones are actively attached to the cell membranes via receptor sites on the outside of the cell, and still others such as sodium and potassium ions are actively pumped across the cell membrane to control how much fluid is inside the cell. The cell membrane is made more rigid by the presence of cholesterol molecules. But overall, the cell membrane still remains a dynamic solvent surface made up largely of phospholipids.

When we are born, we have abundant essential phospholipids such as phosphatidylcholine, which comprises up to 90 percent of the cell membrane. As we age or injury from free radicals or pathogens takes its toll on the cell membrane, that percentage of phosphatidylcholine can decrease down to as low as 10 percent, which is why researchers studied how to make supplements to replace phospholipids. They successfully isolated phospholipids from naturally rich sources like egg yolks and soybean lecithin. Good amounts of phospholipids are also found in sunflower seeds and rapeseeds. Our Phosadyl supplement that we carry is derived from soy lecithin.

Phosadyl supplies 420 mg of that most essential phospholipid, phosphatidylcholine, as well as 100 mg of phosphatidylethanolamine, and 30 mg of phosphatidylinositol. Although many people take soy lecithin as a source of phospholipids, the actual content of essential phospholipids varies in lecithin, so many practitioners, like Dr. Lieberman, prefer standardized supplements.

Uses: Essential phospholipids have been especially helpful in overcoming liver damage and elevated liver enzymes associated with fatty liver. Phospholipid supplements such as Phosadyl, combined with changes in diet and avoiding alcohol, can be surprisingly effective in overcoming elevated liver enzymes and helping to heal the liver. Other uses for phospholipids are to improve cardiovascular problems by reducing the amount of dietary cholesterol that is absorbed by the body, and to supply extra phospholipids for repair from chronic illness or injury. Erectile dysfunction in males has also been helped by phospholipid supplementation. Researchers hoped that phospholipid supplementation could help reverse dementia, since the brain and nervous system are especially rich in phospholipids, but this has not proven to be true, at least not as a single therapy.

January 4, 2018

We’ve always said that Dr. Lieberman is on the leading edge of medicine, and his interest in new ways to combat neurocognitive deficiencies, such as in Alzheimer’s and less severe forms of age-related memory loss, is no exception.

Much of the earlier research on Alzheimer’s Disease centered around the role of heavy metals, especially aluminum, in increasing the production of excessive amounts of amyloid plaque and neurofibrillary tangles in brains of people with Alzheimer’s. More recently, the role of insulin resistance and poor glucose metabolism have been linked to the development of neurocognitive symptoms and dubbed “Type III Diabetes.” Research along these lines has been carried on since at least the late 1990’s, when the Alzheimer’s Research Foundation started educating the public on the effect of poor blood sugar control on the brain.

Newer research, as reported from Massachusetts Institute of Technology (MIT) is centering around actually building brain synapses. Research has progressed to the clinical trial stage with Alzheimer’s patients and has been very encouraging, as reported in the Journal of Alzheimer’s Disease, July 10 online issue. A nutritional protocol is used in this approach, based on supplementing the nutrients Uridine, Choline, and the Omega 3 essential fatty acids DHA. The combination, when used for six months in the clinical trial, was shown to improve both verbal memory recall and performance.

Here at COEM, we now carry all three components of this protocol. The first and newest addition to our supplements, Uridine, 300 mg, is a nucleoside, meaning that it is one of the four building blocks for forming ribonucleic acid (RNA), found in every cell of the body. Another nucleoside, Cytidine, has also been carried by COEM for over 10 years in the form of Cytidine Choline. Choline was specifically used in the above clinical trial with Alzheimer’s patients. We also have carried a very high quality DHA supplement, which is extremely popular on its own for boosting memory, mood, and anti-inflammatory benefits.

If you would like to order any of these supplements from COEM (orders@coem.com), you can use the following guideline to determine how much to order:

Uridine 300 mg, 1 capsule daily

Cytidine Choline (CDP Choline), 1 capsule 2 times daily

DHA, 2 softgels 2 times daily for the 500 mg softgel size, or 1 softgel 2 times daily for the 1000 mg softgel size.

January 3, 2018

The classic picture of someone with food intolerances such as gluten, dairy, or soy intolerance is of a chronically thin, pale, listless individual, hovering on the edge of more normal life. Add allergies to the mix and the classic picture gets worse, with clear impairments manifesting both seasonally and year round.

But what if the patient doesn’t fit the classic picture?

Some of our greatest successes at COEM have been with robust, even overtly obese, individuals who rocket through school, sports, and careers, yet complain of stomach pains, fatigue, joint problems, headaches, muscle aches and a thousand varied symptoms that never seem (at least to outside observers) to slow them down. Who would believe their true level of discomfort in the face of that kind of history? We do.
When weight gain accompanies a cluster of symptoms such as listed above, and diets of many different types are followed for weeks on end without much weight loss or relief, we have to think of food allergies and intolerances. For food allergies, placing the patient in our allergy testing room is often enough to throw off the misconception that favored, much-eaten foods couldn’t possibly be part of the problem. Most patients are astonished to see their arm exhibit the angry, raised, red wheals of full-blown allergy to some of their assuredly healthful food choices, but simply aren’t healthful for their own individual body chemistry. A period of 30 to 60 days avoidance may be enough to regain tolerance to the food if then eaten NO MORE than once every 4 to 7 days, but not always. In some cases, longer avoidance, occasionally permanent avoidance, is necessary in order for the patient to feel truly well.

Unlike allergy, for food intolerance, as we’ve written before, it takes a trial strictly off that entire category of foods for at least 4 weeks and often as much as 12 weeks (3 months) before reaching a true gauge of what benefits could be gained by consistent avoidance. The 3 most common intolerances are to:

1) Gluten—in all foods containing wheat, rye, spelt, kamut, barley, and non-gluten-free oats. Hydrolyzed vegetable protein, soy sauce, flour thickeners, etc. are common hidden sources of gluten.

2) Dairy products—in all foods containing milk, yogurt, sour cream, cheese, cream cheese, whey solids, casein (also sometimes found in soy or rice milk cheeses), etc.

3) Soy products—in all foods containing tofu, soy milk, soy protein, TVP, large amounts of soy lecithin, etc.
Unfortunately, gluten, dairy, and soy all seem to cross-react against each other in terms of the incidence of intolerance and often times all three categories must be strictly avoided for complete relief of all symptoms.

What happens when the intolerant person who has intractable obesity starts avoiding their trigger foods? Often they begin to lose weight, slowly and steadily, without nearly the effort required before. Part of the solution is that their symptoms of fatigue, joint pain, headache, or GI symptoms begin to fade after 4 to 12 weeks on the diet, which gives them much more energy to actively exercise. But mostly it seems that the avoidance of intolerant foods allows the metabolism to heal, the high cortisol levels (triggered by the stress of mal-digested foods) to recede to normal levels, and tendency to insulin resistance to normalize, so weight gain, especially central mid-section obesity, is lost. As the diet is carefully continued, they heal. Now that’s true robustness!

January 3, 2018

Ever struggle to remember something that happened last week? Has your brain ever felt “fried” due to the everyday stresses and overwhelming chores on your to-do list? Ever feel like you would be able to accomplish so much more if you were just able to increase your mental capacity? For many, many years, doctors and scientists have studied the brain in search of improving overall brain function. In their pursuit it was discovered that the brain contains the highest amount of DHA in the entire human body, making it clearly necessary for optimal brain function.

DHA, short for Docosahexaenoic acid, is an omega-3 fatty acid that can be found primarily in the brain, but also in the skin, sperm, testicles, and retina. Found in fish and algae, DHA is a proven protective nutrient that provides multiple brain and cardiovascular benefits. It protects brain tissue from inflammation and damage, stimulates physical changes that promote learning and cognition, and helps to heal injuries as it is converted into protectins (which form at the first signs of damage).

Taking your daily dose of DHA will help to reduce the risk of mild cognitive impairment and will improve focus and memory. However, those low in this essential nutrient could be consequently increasing their risk of cognitive impairment, often associated with Alzheimer’s disease possibly down the road. If you would like to order DHA from the Center, we have it! Just email us at orders@coem.com and Lisa Marie will process it for you. It is available from algae as well as fish, and in different forms, such as liquid and capsules. We even have strawberry flavored gel caps for the younger ones! Feel free to contact us here at the Center with any questions you may have – DHA is highly recommended!

January 2, 2018

Ever struggle to remember something that happened last week? Has your brain ever felt “fried” due to the everyday stresses and overwhelming chores on your to-do list? Ever feel like you would be able to accomplish so much more if you were just able to increase your mental capacity? For many, many years, doctors and scientists have studied the brain in search of improving overall brain function. In their pursuit it was discovered that the brain contains the highest amount of DHA in the entire human body, making it clearly necessary for optimal brain function.

DHA, short for Docosahexaenoic acid, is an omega-3 fatty acid that can be found primarily in the brain, but also in the skin, sperm, testicles, and retina. Found in fish and algae, DHA is a proven protective nutrient that provides multiple brain and cardiovascular benefits. It protects brain tissue from inflammation and damage, stimulates physical changes that promote learning and cognition, and helps to heal injuries as it is converted into protectins (which form at the first signs of damage).

Taking your daily dose of DHA will help to reduce the risk of mild cognitive impairment and will improve focus and memory. However, those low in this essential nutrient could be consequently increasing their risk of cognitive impairment, often associated with Alzheimer’s disease possibly down the road. If you would like to order DHA from the Center, we have it! Just email us at orders@coem.com and Lisa Marie will process it for you. It is available from algae as well as fish, and in different forms, such as liquid and capsules. We even have strawberry flavored gel caps for the younger ones! Feel free to contact us here at the Center with any questions you may have – DHA is highly recommended!