We’ve always said that Dr. Lieberman is on the leading edge of medicine, and his interest in new ways to combat neurocognitive deficiencies, such as in Alzheimer’s and less severe forms of age-related memory loss, is no exception.
Much of the earlier research on Alzheimer’s Disease centered around the role of heavy metals, especially aluminum, in increasing the production of excessive amounts of amyloid plaque and neurofibrillary tangles in brains of people with Alzheimer’s. More recently, the role of insulin resistance and poor glucose metabolism have been linked to the development of neurocognitive symptoms and dubbed “Type III Diabetes.” Research along these lines has been carried on since at least the late 1990’s, when the Alzheimer’s Research Foundation started educating the public on the effect of poor blood sugar control on the brain.
Newer research, as reported from Massachusetts Institute of Technology (MIT) is centering around actually building brain synapses. Research has progressed to the clinical trial stage with Alzheimer’s patients and has been very encouraging, as reported in the Journal of Alzheimer’s Disease, July 10 online issue. A nutritional protocol is used in this approach, based on supplementing the nutrients Uridine, Choline, and the Omega 3 essential fatty acids DHA. The combination, when used for six months in the clinical trial, was shown to improve both verbal memory recall and performance.
Here at COEM, we now carry all three components of this protocol. The first and newest addition to our supplements, Uridine, 300 mg, is a nucleoside, meaning that it is one of the four building blocks for forming ribonucleic acid (RNA), found in every cell of the body. Another nucleoside, Cytidine, has also been carried by COEM for over 10 years in the form of Cytidine Choline. Choline was specifically used in the above clinical trial with Alzheimer’s patients. We also have carried a very high quality DHA supplement, which is extremely popular on its own for boosting memory, mood, and anti-inflammatory benefits.
If you would like to order any of these supplements from COEM (orders@coem.com), you can use the following guideline to determine how much to order:
Uridine 300 mg, 1 capsule daily
Cytidine Choline (CDP Choline), 1 capsule 2 times daily
DHA, 2 softgels 2 times daily for the 500 mg softgel size, or 1 softgel 2 times daily for the 1000 mg softgel size.