Steroid Metabolism: Modification with Foods and Nutrients

MODIFICATION OF STEROID METABOLISM WITH FOODS, MINERALS, PHYTOCHEMICALS AND A VITAMIN

Jonathan V. Wright, M.D.
Tahoma Clinic, Kent, WA


ABSTRACT: Options available to practitioners for safe, effective modulation of steroid metabolism are increasing. Brassica vegetables, soy, and flaxseed have all been shown to favorably influence the 2/16a hydroxyestrogen ratio (a “risk factor” for estrogen related cancers.


Supplemental indole-3-carbinol and di-indolylmethane do the same. Vitamin A increases low levels of 17-B estradiol. Black cohosh can also stimulate increased estrogen production, while Vitex may favorably increase progesterone levels. Chrysin in many cases inhibits “abnormal” aromatization of androgens to estrogens. Boron raises circulating levels of estrogens and progesterone in postmenopausal women, and testosterone levels in men in their 50s and upwards. respectively.


Examples of the little-known observation that iodine increases the complete metabolization of estrogens to estriol will be shown.


The novel observation of estrogen hypermetabolization and hyperexcretion, clinical manifestations of this problem, and correction of both symptomatic and laboratory manifestations by cobalt will be described, with examples.