A Major Giant Step

December 12, 2014

AMPK – A Major Giant Step

Epidemiologists discovered that diabetics who were taking a prescription drug called Metformin, derived from the French lilac, had a lower incidence of cancer than non-diabetic, normal, healthy people. Not only was it able to lower cancer rates, but it also reversed aging, degenerative diseases, insulin resistance, and excess belly fat.

When we are young, our cell metabolism converts glucose and fatty acids to energy, instead of them being stored as body fat. As we age, we are no longer able to do that. Scientists have now discovered the secret of Metformin is its ability to activate an enzyme called AMPK (adenosine monophosphate-activated protein kinase), which can turn back on our youthful cellular metabolism. (1)

What is even more exciting is that two plant-derived extracts can do it even better. They are the Chinese herb Gynostemma Pentaphyllum and Trans-tiliroside extracted from rose hips.



AMP-activated protein kinase

When AMPK is activated, cells go into a survival mode, making and storing no new fat, while burning up available fat and pumping glucose in from the blood for additional energy. (2) It builds new mitochondria, our cellular powerhouses that produce energy, and recycles damaged or dysfunctional proteins. (3)

To activate AMPK normally requires severe calorie restriction and rigorous exercise, but Metformin and these two natural plant extracts can activate AMPK without starving or exercising.

Capitalizing on this giant step can:


  1. Increase lifespan
  2. Lower blood sugar
  3. Decrease fat synthesis
  4. Increase burning of body fat
  5. Reduce blood triglycerides
  6. Reduce cholesterol and LDL cholesterol
  7. Decrease body weight and belly fat
  8. Decrease insulin resistance and diabetes
  9. Reduce the incidence of cancer


Wow is all I can say!


Some physicians recommend their healthy patients take Metformin 500 mg twice daily. I would prefer using the natural plant extracts, which are even more active than the drug.


As you are aware, I like to pass on information on new and exciting nutrients that have health-promoting properties as the data and feedback come in to support the use of the product.


This holiday season you may want to consider adding one or two of these amazing life and health-promoting nutrients to your holiday gift-giving list.


AMPK Activator, 90 capsules – $40 per bottle

Dosage: Two capsules with breakfast. 
One capsule with lunch.


To order a supply of AMPK Activator, or any of the other nutrients from COEM, send an e-mail to ORDERS@COEM.COM with the following information.

  • Name
  • Address
  • City/State/Zip
  • Number of bottles you wish to order
  • Credit Card Information (you call in this info if you wish)
  • If you are picking up your order at our office, please let us know as well


Please allow 5-7 business days to process your order.




(1) Salminen A, Kaarniranta K, AMP-activated protein kinase (AMPK) controls the aging process via an integrated signaling network. Ageing Res Rev. 2012 APr;11(2):230-41.


(2) Luo Z, Zang M, Guo W. AMPK as a metabolic tumor suppressor: control of metabolism and cell growth. Future Oncol. 2010 Mar;6(3):457-70.


(3) Zong H, Ren JM, Young LH,Pypaert M, Mu J, Birnbaum MJ, et al. AMP kinase is required for mitochondrial biogensis in skeletal muscle in response to chronic energy deprivation. Proc Natl Acad Sci USA. 2002 Dec 10;99(25):15983-7.


Yours in health,


Allan D. Lieberman, M.D., F.A.A.E.M.


Medical Director


Center for Occupational & Environmental Medicine

December 12, 2014 

Posted in Health Alerts